The cell penetrating peptide market refers to the industry involved in the production, development, and commercialization of cell penetrating peptides (CPPs). CPPs are short peptides that have the ability to cross cellular membranes and deliver various molecules, such as drugs, genes, or imaging agents, into the body. The ability of CPPs to interact with and cross the cellular membrane via a variety of routes makes them special. CPPs can be created artificially by altering their amino acid sequences or taken from natural sources.
Due to their potential uses in a number of fields, including the treatment of cancer, gene therapy, and regenerative medicine, peptides have drawn a lot of interest in the field of drug delivery and therapeutics. Recent developments in peptide synthesis methods, improved knowledge of peptide & cellular interactions, and the rising need for efficient drug delivery systems are expected to contribute to the growth of cell penetrating peptide market. Moreover, pharmaceutical corporations and academic research centers are participating in the market as active CPP research and development organizations. For instance, in April 2023 , the next generation of gene and cell therapies could potentially be powered by an improved gene editing technique developed by Penn Medicine. In comparison to existing techniques, the CRISPR-Cas gene editing methodology based on unique cell-penetrating peptides promises benefits for modifying the cellular genomes.
The cell penetrating peptides have shown promising results in the development of transgenic plants. For instance, as per the article published by Multidisciplinary Digital Publishing Institute in the Journal Molecules in April 2023, CPPs were used to transfer DNA to plants. To improve DNA interaction and stabilization in transgenesis, CPPs were created and functional group alterations were made. They may transport payloads either covalently or noncovalent and internalize CPP/cargo complexes into cells either through endocytosis or direct membrane translocation. They provided methods for transfection and had an impact on transgene expression at subcellular locations such plastids, mitochondria, and the nucleus.
North America is estimated to dominate the cell penetrating peptides market owing to substantial research and development, research collaborations amongst pharmaceutical companies & academic institutions, and massive investments. Furthermore, Europe is also expected to register considerable CAGR during the forecast period. Growing research activities in the region is expected to play a major role in Europe market. For instance, in July 2022, Altamira Therapeutic announced a results of its study on cell-penetrating peptide, which can be utilized as an effective platform for cancer therapy.
Segments |
Details |
Type |
Protein-based CPPs (TAT peptide, Penetratin, Antp), Peptide-based, CPPs (Oligoarginine peptide, Polysrginine peptide, Transportan) |
Application |
Drug Delivery, Gene Delivery, Diagnostics, Molecular Imaging, Others (Vaccine development, Antimicrobial Therapy) |
End user |
Pharmaceutical and Biotechnology Company, Contract Research Organization (CROs), Hospitals and Clinics |
Region |
North America, Europe, Asia Pacific, Latin America, Middle East & Africa |
Major companies operating in the market include PolyPeptide Group, Cupidpeptides, Alta Bioscience Ltd, AnaSpec, Peptomyc SL, Creative Peptides, and Bachem Group.
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